Linked Life Data

6266932

Source:http://linkedlifedata.com/resource/pubmed/id/6266932

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1981-10-14
pubmed:abstractText
In an attempt to provide better assessment of human chorionic gonadotropin beta-subunit (hCG-beta) secretion in pregnant women, a method was developed for complete removal of hCG by porcine-purified receptors before measurement of the free hCG-beta subunit by radioimmunoassay. Blood samples of 111 pregnant women were collected and the following results were obtained: (1) Extensive removal (over 96%) of hCG allows quantitative determination of the free hCG-beta subunit by a specific radioimmunoassay. Our data demonstrate the presence of circulating hCG-beta subunit during pregnancy, a fact that was still under controversy until now. (2) In contrast with the hCG profile drug during pregnancy the free hCG-beta subunit exhibits a plasma concentration peak (400 +/- 132 ng/ml; mean +/- 1 SD) at the 12th-13th week, indicating that the changes in plasma levels of intact hCG and free hCG-beta subunit are unrelated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0378-7346
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
81-92
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Demonstration of plasma human chorionic gonadotropin beta-subunit during pregnancy using LH-hCG receptors from immature porcine testis.
pubmed:publicationType
Journal Article