Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1981-8-10
pubmed:abstractText
Seventy-six consecutive patients presenting to a genital herpes simplex virus (HSV) clinic were enrolled in a study comparing viral isolation (VI), indirect immunoperoxidase (indirect IP), and direct immunofluorescence (direct FA) techniques for the detection of HSV antigen. Of the 76 patients, 61 (80%) demonstrated HSV by VI, compared with 66% by indirect IP and 55% by direct FA (P less than 0.05). Genital lesions from nine patients demonstrated HSV antigen by direct FA or indirect IP but were VI negative; eight of nine patients had subsequent episodes of genital HSV confirmed by VI. During the vesicular-pustular stage of the disease, VI was positive in 90%, indirect IP was positive in 76%, and direct FA was positive in 71% of the lesions, whereas with ulcerative lesions, VI was positive in 72%, indirect IP was positive in 55%, and direct FA was positive in 38%. These commercially available rapid viral diagnostic techniques are specific and useful, if adequate specimens are obtained from early genital lesions.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-180196, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-194157, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-198656, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-201662, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-211414, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-221993, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-223095, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-351401, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-353227, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-4315623, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-4315624, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-4327295, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-4330477, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-4348495, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-4349660, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-4361339, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-4370826, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-4869846, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-5818824, http://linkedlifedata.com/resource/pubmed/commentcorrection/6263945-73546
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
913-8
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Comparison of viral isolation, direct immunofluorescence, and indirect immunoperoxidase techniques for detection of genital herpes simplex virus infection.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.