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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1981-8-10
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pubmed:abstractText |
Carriers of Z-gene alpha 1-antitrypsin deficiency (A-1-ATD) have characteristic periodic acid Schiff (PAS) positive diastase resistant globules in hepatocytes. In order to determine a possible relationship between Z-gene A-1-ATD and small cell carcinoma of the lung (SCCL), we examined liver blocks from 88 consecutive autopsies performed on patients with SCCL and from a control group of 88 patients with carcinoma not primarily located in the lung or the liver. Histological evidence of Z-gene-A-1-ATD was 4.5% in both groups, corresponding to the expected frequency of Z-gene carriers in a Scandinavian population. It is therefore unlikely that Z-gene A-1-ATD has a role in the development of SCCL.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0106-4339
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-10
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6263662-Adult,
pubmed-meshheading:6263662-Aged,
pubmed-meshheading:6263662-Carcinoma, Small Cell,
pubmed-meshheading:6263662-Female,
pubmed-meshheading:6263662-Genes,
pubmed-meshheading:6263662-Humans,
pubmed-meshheading:6263662-Liver,
pubmed-meshheading:6263662-Lung Neoplasms,
pubmed-meshheading:6263662-Male,
pubmed-meshheading:6263662-Middle Aged,
pubmed-meshheading:6263662-Periodic Acid-Schiff Reaction,
pubmed-meshheading:6263662-alpha 1-Antitrypsin,
pubmed-meshheading:6263662-alpha 1-Antitrypsin Deficiency
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pubmed:year |
1981
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pubmed:articleTitle |
Histological examination for Z-gene alpha 1-antitrypsin deficiency in small cell anaplastic carcinoma of the lung.
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pubmed:publicationType |
Journal Article
|