Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1981-7-23
pubmed:abstractText
Cytomegalovirus (CMV) and herpes simplex virus (HSV) antibodies were detected by a modified passive haemagglutination (PHA) technique. The main features of this modification are the use of a simpler method for the removal of nonspecific sheep agglutinins in the sera, the deployment of commercially available CMV and HSV antigens, and a different sucrose density gradient (SDG) system for the separation of IgM from IgG. The modified procedure proved to be a reliable, specific, and sensitive technique in detecting antibodies to CMV and HSV in both whole serum and in the separated IgM and IgG fractions. It was as reliable as the complement-fixation (CF) test when applied in seroepidemiological studies and in the detection of antibodies in cord serum. Preliminary data are provided which suggest that the combination of SDG and PHA may prove to be a more reliable system for the detection of exclusion of CMV-specific IgM than an enzyme-linked immunosorbent assay (ELISA).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0146-6615
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
287-93
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
A modified passive-haemagglutination technique for the detection of cytomegalovirus and herpes simplex virus antibodies: application in virus-specific IgM diagnosis.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't