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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1981-7-9
|
pubmed:abstractText |
The effect of the aging process on gastric emptying was studied in 11 elderly subjects (mean age, 77) and in 7 young healthy volunteers (mean age, 26). Gastric emptying rates were assessed by a modified sequential scinti-scanning technique after administration of the nonabsorbable chelated radiopharmaceutical 99mTc-DTPA. The rate of emptying, expressed as half-time (T 1/2e) in minutes, was significantly longer (p less than 0.001) in the elderly subjects (mean apparent T 1/2e = 123.23 min) compared to the young healthy volunteers (mean apparent T 1/2e = 49.69 min). Clinical implications of these findings are discussed, particularly with respect to the rate and extent of drug absorption in elderly persons.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0002-8614
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
29
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
201-5
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pubmed:dateRevised |
2008-3-10
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pubmed:meshHeading |
pubmed-meshheading:6262396-Administration, Oral,
pubmed-meshheading:6262396-Adult,
pubmed-meshheading:6262396-Aged,
pubmed-meshheading:6262396-Aging,
pubmed-meshheading:6262396-Female,
pubmed-meshheading:6262396-Gastric Emptying,
pubmed-meshheading:6262396-Humans,
pubmed-meshheading:6262396-Male,
pubmed-meshheading:6262396-Pentetic Acid,
pubmed-meshheading:6262396-Sodium Pertechnetate Tc 99m,
pubmed-meshheading:6262396-Technetium,
pubmed-meshheading:6262396-Technetium Tc 99m Pentetate,
pubmed-meshheading:6262396-Time Factors
|
pubmed:year |
1981
|
pubmed:articleTitle |
Gastric emptying rate in the elderly: implications for drug therapy.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|