Linked Life Data

6259553

Source:http://linkedlifedata.com/resource/pubmed/id/6259553

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1981-5-28
pubmed:abstractText
To further elucidate to what extent minor sellar roentgenological changes imply the presence of a microadenoma or other histopathological findings in the pituitary gland, an autopsy series of 205 cases was investigated. Plain sellar films and multidirectional tomograms in frontal and lateral projections were obtained and the pituitary gland was histopathologically examined after being serial sectioned. Sloping of the sellar floor amounting to 2-14 degrees was found in 39 cases and minor cortical changes and configuration variations (locally thinner cortical layer, erosion and bulging) were seen in 23 cases. Histopathology revealed a solitary tumour in the anterior lobe in three cases and focal nodular hyperplasia in a fourth case. The diameter of these nonencapsulated 'adenomas' varied between 3 and 5 mm. Small cysts were a fairly common finding and fibrous tissue was present in about every second gland. No correlation was found between the roentgenological changes of the sella and histopathological findings in the gland. It was concluded that the type of roentgenological sellar findings described should be considered as normal variations without pathological significance when diagnosing a pituitary microadenoma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0028-3940
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-65
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
A parallel study of the roentgen anatomy of the sella turcica and the histopathology of the pituitary gland in 205 autopsy specimens.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't