rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5796
|
pubmed:dateCreated |
1981-4-21
|
pubmed:abstractText |
A gene chimaera of the first exon from simian virus 40 (SV40) sequences coding for T antigen placed upstream from the third exon from mouse beta-globin, and separated by the resultant new chimaeric intron, was cloned into a bacterial plasmid. When transfected into monkey cells, the gene chimaera was transcribed, polyadenylated and spliced using the donor splice site from SV40 and the acceptor splice site from mouse beta-globin. This result suggests that a donor site from one gene can be spliced to an acceptor site from another gene.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Viral, Tumor,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Recombinant,
http://linkedlifedata.com/resource/pubmed/chemical/Globins,
http://linkedlifedata.com/resource/pubmed/chemical/Nucleic Acid Precursors,
http://linkedlifedata.com/resource/pubmed/chemical/Poly A,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0028-0836
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
29
|
pubmed:volume |
289
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
378-82
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:6258077-Antigens, Neoplasm,
pubmed-meshheading:6258077-Antigens, Viral,
pubmed-meshheading:6258077-Antigens, Viral, Tumor,
pubmed-meshheading:6258077-Base Sequence,
pubmed-meshheading:6258077-Chimera,
pubmed-meshheading:6258077-DNA, Recombinant,
pubmed-meshheading:6258077-Globins,
pubmed-meshheading:6258077-Nucleic Acid Precursors,
pubmed-meshheading:6258077-Poly A,
pubmed-meshheading:6258077-RNA, Messenger,
pubmed-meshheading:6258077-Simian virus 40,
pubmed-meshheading:6258077-Transcription, Genetic
|
pubmed:year |
1981
|
pubmed:articleTitle |
A gene chimaera of SV40 and mouse beta-globin is transcribed and properly spliced.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|