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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1981-1-26
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pubmed:abstractText |
A total of 519 colorectal carcinomas were examined for the presence or absence of mucinous differentiation by means of microscopical morphometry. Of these, 28% had objectively measurable amounts of mucinous tumour epithelium. Tumours with > 50% mucinous areas (14%) had significantly poorer prognosis than non-mucinous in stages A and C, while mucinous differentiation did not correlate with prognosis in stages B and D. Lymph nodes regional to mucinous tumours had significantly less paracortical response, and those with < 50% mucinous differentiation, significantly less perivascular lymphocyte cuffing at the tumour margins. These lymph node and stromal compartments are putative T-lymphocyte areas, and hence our findings suggest that mucinous tumours are either less stimulatory or perhaps inhibitory of cell-mediated immunity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
pubmed:issn |
0031-3025
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
439-47
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6253864-Adenocarcinoma, Mucinous,
pubmed-meshheading:6253864-Colonic Neoplasms,
pubmed-meshheading:6253864-Female,
pubmed-meshheading:6253864-Humans,
pubmed-meshheading:6253864-Lymph Nodes,
pubmed-meshheading:6253864-Male,
pubmed-meshheading:6253864-Middle Aged,
pubmed-meshheading:6253864-Neoplasm Staging,
pubmed-meshheading:6253864-Prognosis,
pubmed-meshheading:6253864-Rectal Neoplasms
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pubmed:year |
1980
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pubmed:articleTitle |
Mucinous colorectal carcinoma: immunopathology and prognosis.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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