rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1981-1-26
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pubmed:abstractText |
Circadian stage-dependent effects characterize synthetic ACTH 1-17 preparation (HOE 433 = Synchrodyn 1-17), tested in mice and rats, with reference notably to corticosterone and aldosterone production in vitro and to the behavior of rhythms in these two corticoids as an aspect of the adrenal cortical pacemaker of the circadian system. The possibility to advance or delay the rhythm in serum corticosterone by ACTH 1-17 also is demonstrated, as is a differential behavior of the circadian rhythm in serum aldosterone. Differences in timing of circadian corticosterone and aldosterone responses also are described and await further scrutiny for ultradian and infradian (notably circannual) modulation.
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pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0390-0037
|
pubmed:author |
pubmed-author:BerkLL,
pubmed-author:BrownHH,
pubmed-author:CulleyDD,
pubmed-author:HalbergEE,
pubmed-author:HalbergFF,
pubmed-author:HautJJ,
pubmed-author:HrusheskyWW,
pubmed-author:LakatuaDD,
pubmed-author:LevyVV,
pubmed-author:MelbyJJ,
pubmed-author:PaulyJJ,
pubmed-author:Sanchez de la PeñaSS,
pubmed-author:SanchezEE,
pubmed-author:SchevingL ELE,
pubmed-author:SothernR BRB,
pubmed-author:WilsonTT
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pubmed:issnType |
Print
|
pubmed:volume |
7
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
211-26
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:6253238-Adrenocorticotropic Hormone,
pubmed-meshheading:6253238-Aldosterone,
pubmed-meshheading:6253238-Animals,
pubmed-meshheading:6253238-Circadian Rhythm,
pubmed-meshheading:6253238-Corticosterone,
pubmed-meshheading:6253238-Dose-Response Relationship, Drug,
pubmed-meshheading:6253238-Female,
pubmed-meshheading:6253238-Male,
pubmed-meshheading:6253238-Mice,
pubmed-meshheading:6253238-Mice, Inbred BALB C,
pubmed-meshheading:6253238-Sex Factors,
pubmed-meshheading:6253238-Structure-Activity Relationship
|
pubmed:articleTitle |
Time-varying effects in mice and rats of several synthetic ACTH preparations.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|