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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1981-1-26
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pubmed:abstractText |
Ab-MuLV transforms mouse 3T3 fibroblasts, macrophages, and lymphocytes, which have properties of immature cells in the B-lymphocyte differentiation pathway. Differences in expression of intracellular immunoglobulin and surface antigens the lymphoma lines suggest that more than one B-lymphocyte differentiation stage may be transformed, each of which must be before the B lymphocyte acquires cell-surface immunoglobulin receptors for antigen and antigen sensitivity. The plasmacytomas induced by Ab-MuLV plus pristane tested thus far show no evidence of infection by Ab-MuLV. The transformation of these immunoglobulin-secreting cells may be due to causes other than the transforming elements of the Ab-MuLV genome.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0091-7451
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44 Pt 2,
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1187-94
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6253193-Abelson murine leukemia virus,
pubmed-meshheading:6253193-Animals,
pubmed-meshheading:6253193-Antigens, Surface,
pubmed-meshheading:6253193-B-Lymphocytes,
pubmed-meshheading:6253193-Cell Differentiation,
pubmed-meshheading:6253193-Cell Line,
pubmed-meshheading:6253193-Cell Transformation, Viral,
pubmed-meshheading:6253193-Leukemia, Experimental,
pubmed-meshheading:6253193-Leukemia Virus, Murine,
pubmed-meshheading:6253193-Lymphoma,
pubmed-meshheading:6253193-Macrophages,
pubmed-meshheading:6253193-Mice,
pubmed-meshheading:6253193-Plasmacytoma
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pubmed:year |
1980
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pubmed:articleTitle |
Transformation by Abelson murine leukemia virus: properties of the transformed cells.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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