Linked Life Data

6249494

Source:http://linkedlifedata.com/resource/pubmed/id/6249494

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8 Pt 2
pubmed:dateCreated
1980-10-21
pubmed:abstractText
During the past 30 years, the rapidly developing and changing concepts and technology of the discipline of immunobiology have been applied to studies in oncology. After the definitive demonstration of so-called tumor-specific transplantation antigens in chemically and virally induced tumors in syngeneic rodent and murine species, numerous efforts were then directed toward the demonstration of comparable materials in human tumors. After a number of false starts in an overzealous search for a marker that would serve as a panacea for human cancer diagnosis, more rational approaches have been taken to the problem and valuable information from the points of view of both the cell biologist and clinical oncologist has been forthcoming. The present paper presents an overview of human tumor antigens as biological markers of tumor growth. Reference is made to the fact that normally occurring biological materials of known function that are qualitatively and/or quantitatively altered during the process of malignant transformation may be most useful in the diagnosis and management of the cancer patient. The role of the presently available radioimmunoassays for carcinoembryonic antigen in clinical medicine is outlined.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0008-5472
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2973-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Historical development and potential uses of tumor antigens as markers of human cancer growth.
pubmed:publicationType
Journal Article