| pubmed-article:6248281 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6248281 | lifeskim:mentions | umls-concept:C0162371 | lld:lifeskim |
| pubmed-article:6248281 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:6248281 | lifeskim:mentions | umls-concept:C0000530 | lld:lifeskim |
| pubmed-article:6248281 | lifeskim:mentions | umls-concept:C0086438 | lld:lifeskim |
| pubmed-article:6248281 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
| pubmed-article:6248281 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:6248281 | pubmed:dateCreated | 1980-9-23 | lld:pubmed |
| pubmed-article:6248281 | pubmed:abstractText | The 5'-nucleotidase (5'-N) deficiency on circulating mononuclear cells of patients with 'common variable' hypogammaglobulinaemia (CV-H) was shown to be the result of one or more of three factors: reduced T cell 5'-N activity, a reduced percentage of circulating B cells, and a low B cell 5'-N activity. A lack of circulating B lymphocytes, together with a low T cell 5'-N activity in some cases, was found to be responsible for the deficiency of lymphocyte 5'-N in patients with X-linked hypogammaglobulinaemia (X-H). The low levels of 5'-N activity in CV-H and X-H patients were not due to abnormal compartmentalization of the enzyme, altered enzyme kinetics, or the presence of a regulatory factor. Cord Blood B and T cells have a lower 5'-N activity than adult lymphocytes. The patient and cord blood data are discussed in relation to the stage of cellular maturity. | lld:pubmed |
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| pubmed-article:6248281 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6248281 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6248281 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:6248281 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6248281 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:6248281 | pubmed:issn | 0009-9104 | lld:pubmed |
| pubmed-article:6248281 | pubmed:author | pubmed-author:AshersonG LGL | lld:pubmed |
| pubmed-article:6248281 | pubmed:author | pubmed-author:WebsterA DAD | lld:pubmed |
| pubmed-article:6248281 | pubmed:author | pubmed-author:Platts-MillsT... | lld:pubmed |
| pubmed-article:6248281 | pubmed:author | pubmed-author:JohnsonS MSM | lld:pubmed |
| pubmed-article:6248281 | pubmed:author | pubmed-author:de GastG CGC | lld:pubmed |
| pubmed-article:6248281 | pubmed:author | pubmed-author:RoweMM | lld:pubmed |
| pubmed-article:6248281 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6248281 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:6248281 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6248281 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6248281 | pubmed:pagination | 337-43 | lld:pubmed |
| pubmed-article:6248281 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6248281 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:6248281 | pubmed:articleTitle | Lymphocyte 5'-nucleotidase in primary hypogammaglobulinaemia and cord blood. | lld:pubmed |
| pubmed-article:6248281 | pubmed:publicationType | Journal Article | lld:pubmed |
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