Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1980-8-15
pubmed:abstractText
Miniature endplate currents, recorded from voltage-clamped toad sartorius muscle fibers in solutions containing ammonium ions substituted for sodium ions, were increased in amplitude and decayed exponentially with a slower time constant than in control (Na) solution. The peak conductance of miniature endplate currents was also greater in ammonium solutions. The acetylcholine null potential was -2.8 +/- 0.8 mV in control solution, and shifted to 0.9 +/- 1.6 mV in solutions in which NH4Cl replaced half the NaCl. In solutions containing NH4Cl substituted for all the NaCl, the null potential was 6.5 +/- 1.3 mV. Single channel conductance and average channel lifetime were both increased in solutions containing ammonium ions. The exponential relationship between the time constant of decay of miniature endplate currents or channel lifetime and membrane potential was unchanged in ammonium solutions. A slight but consistent increase in peak conductance during miniature endplate currents and single channel conductance was seen as membrane potential became more positive (depolarized) in both control and ammonium solutions. Net charge transfer was greater in ammonium solutions than in control solution, whether measured during a miniature endplate current or through a single channel. The results presented here are consistent with an endplate channel model containing high field strength, neutral sites.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-13491248, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-13672685, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-13811119, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-14426120, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-1460, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-18128147, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-192885, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-19873371, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-203674, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-212556, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-238230, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-300788, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-305002, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-312319, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-313017, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-379345, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-413051, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-424757, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-4543940, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-4585227, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-458642, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-460691, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-460692, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-4614, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-4628385, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-5025743, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-5445879, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-5579685, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-587, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-6059652, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-671284, http://linkedlifedata.com/resource/pubmed/commentcorrection/6247424-6767026
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-1295
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
589-613
pubmed:dateRevised
2010-9-13
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Effects of ammonium ions on endplate channels.
pubmed:publicationType
Journal Article, In Vitro