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rdf:type |
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lifeskim:mentions |
umls-concept:C0001041,
umls-concept:C0003577,
umls-concept:C0030685,
umls-concept:C0039062,
umls-concept:C0205396,
umls-concept:C0231239,
umls-concept:C0332128,
umls-concept:C0391871,
umls-concept:C0521116,
umls-concept:C0680255,
umls-concept:C0936012,
umls-concept:C1283071,
umls-concept:C1963578
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pubmed:issue |
3
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pubmed:dateCreated |
1980-7-22
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pubmed:abstractText |
Quantal events have been analyzed at a neuro-neuronal synapse of Aplysia where the nature of the transmitter is established and both presynaptic and postsynaptic neurons are identified and can be voltage-clamped. Prolonged depolarizations were applied to the presynaptic neuron, which gave rise in the postsynaptic cell to a current response characterized by current fluctuations or noise. Acetylcholine was also applied ionophoretically on the same postsynaptic cell. Amplitude and time course of miniature currents and acetylcholine-activated chloride channels of the same cell were examined by using a current fluctuation analysis. It was estimated that one presynaptic spike releases about 180 quanta, each opening 500 chloride channels.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-1086359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-1245231,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-13919241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-13919847,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-144899,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-15274,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-171379,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-171380,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-174144,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-181197,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-210881,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-212550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-212551,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-214543,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-225472,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-25388,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-360942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-4303656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-4370647,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-4373738,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-4377745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-4383089,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-4537943,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-5071933,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-5564045,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-5723516,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-5965569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-672992,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6246498-974759
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0027-8424
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
77
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1661-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1980
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pubmed:articleTitle |
Quantal release of acetylcholine examined by current fluctuation analysis at an identified neuro-neuronal synapse of Aplysia.
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pubmed:publicationType |
Journal Article
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