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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1985-5-15
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pubmed:abstractText |
An antiserum specific for atriopeptin was used to characterize and localize atriopeptin-like immunoreactive material in rat atrium by radioimmunoassay and immunohistochemical techniques. The antiserum recognizes atriopeptin I, atriopeptin III, and alpha-human atrial natriuretic polypeptide, but does not recognize met-enkephalin, cholecystokinin, dynorphin A, bradykinin, substance P, or beta-endorphin. A high content of atriopeptin was found in crude extracts of rat atria, as compared to ventricles, and the atriopeptin-like immunoreactive material was found to be located exclusively in granules within atrial cardiocytes. Fractionation of the immunoreactive material by gel filtration and reverse-phase HPLC revealed the presence of multiple atriopeptins.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0196-9781
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1173-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6241672-Animals,
pubmed-meshheading:6241672-Antibody Specificity,
pubmed-meshheading:6241672-Atrial Natriuretic Factor,
pubmed-meshheading:6241672-Heart Atria,
pubmed-meshheading:6241672-Histocytochemistry,
pubmed-meshheading:6241672-Immunochemistry,
pubmed-meshheading:6241672-Muscle Proteins,
pubmed-meshheading:6241672-Rats
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pubmed:articleTitle |
Characterization and localization of atriopeptin in rat atrium.
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pubmed:publicationType |
Journal Article,
Comparative Study
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