Linked Life Data

624146

Source:http://linkedlifedata.com/resource/pubmed/id/624146

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1978-4-17
pubmed:abstractText
A micro-Fick method has been developed to measure the O2 consumption of different regions of an organ. The method was tested in isolated dog gracilis muscle and consisted of microspectrophotometric determination of arterial and venous O2 saturation in quick frozen tissue to determine O2 extraction and flow measured with 85Sr-labeled microspheres, with O2 consumption calculated from the product. This was compared to electromagnetically measured flow and O2 extraction determined by Van Slyke or CO-oximeter. The accuracy of the new measurement was at worst 8.7% for O2 consumption over the range tested in a single muscle. In the hearts of anesthetized open-chest dogs, right ventricular O2 consumption, 7.1 +/- 0.9 ml O2/min per 100 g, was significantly lower than left, 11.0 +/- 0.4. This gradient was related to a blood flow difference. Right ventricular base had a 51% lower O2 consumption than right ventricular apex. In the left ventricle, subepicardial O2 consumption, 9.5 +/- 0.7, was lower than that of the subenocardium, 12.1 +/- 0.7. This difference was related to a difference in O2 extraction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0009-7330
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
394-401
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Quantitative determination of regional oxygen consumption in the dog heart.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.