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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
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pubmed:dateCreated |
1985-1-3
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|
pubmed:abstractText |
The 19-nor-steroid RU-486 is an antagonist of glucocorticosteroids acting competitively at the receptor level. Pharmacological and endocrinological studies have already shown that RU-486 is able to reverse glucocorticosteroid effects. The present study shows that RU-486 can counteract the inhibitory effect of glucocorticosteroids in two highly corticoid-sensitive in vitro immune responses: murine in vitro antibody response and human autologous mixed lymphocyte reaction.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:issn |
0165-2478
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pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:volume |
8
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|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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|
pubmed:pagination |
183-6
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|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6238907-Animals,
pubmed-meshheading:6238907-Antibody Formation,
pubmed-meshheading:6238907-B-Lymphocytes,
pubmed-meshheading:6238907-Dexamethasone,
pubmed-meshheading:6238907-Estrenes,
pubmed-meshheading:6238907-Female,
pubmed-meshheading:6238907-Glucocorticoids,
pubmed-meshheading:6238907-Hemolytic Plaque Technique,
pubmed-meshheading:6238907-Humans,
pubmed-meshheading:6238907-Hydrocortisone,
pubmed-meshheading:6238907-Immunosuppressive Agents,
pubmed-meshheading:6238907-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:6238907-Male,
pubmed-meshheading:6238907-Mice,
pubmed-meshheading:6238907-Mice, Inbred DBA,
pubmed-meshheading:6238907-Mifepristone,
pubmed-meshheading:6238907-Receptors, Glucocorticoid,
pubmed-meshheading:6238907-Spleen,
pubmed-meshheading:6238907-T-Lymphocytes
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|
pubmed:year |
1984
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|
pubmed:articleTitle |
Inhibition of in vitro immunosuppressive effects of glucocorticosteroids by a competitive antagonist RU-486.
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pubmed:publicationType |
Journal Article
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