Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-1-17
pubmed:abstractText
Two subpopulations of rabbit spleen and mesenteric lymph node T cells were identified by a monoclonal antibody, 8AC8. These subpopulations were separated on the flow cytometer and were analysed for their response to T cell mitogens and antigens, their responsiveness in mixed lymphocyte cultures, and their ability to function as cytotoxic effector cells. The 8AC8+ T cell subpopulation contained cells highly responsive to T cell mitogens, to antigen, and to allogeneic or autologous stimuli in a mixed lymphocyte reaction. In contrast, the 8AC8- T cell subpopulation was non-responsive to T cell mitogens, and responded, poorly to antigen, and to allogeneic and autologous stimuli in an MLR. Both the 8AC8+ and 8AC8- subpopulations exhibited xenogenic cytotoxic effector function. Thus, the 8AC8 MAb identified a subpopulation of mature differentiated rabbit T cells; these 8AC8+ cells share many of the characteristics of the human OKT4 helper/inducer T cell subpopulation.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-105045, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-1083869, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-1084783, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-15036, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-181845, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-308967, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-315070, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-315435, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-4578140, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-4596694, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-5047371, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-6201724, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-6600269, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-6605862, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-6756939, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-6804369, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-68704, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-7040945, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-779969, http://linkedlifedata.com/resource/pubmed/commentcorrection/6238903-796385
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0019-2805
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
659-67
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Characterization of functionally distinct subpopulations of rabbit T lymphocytes.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.