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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1984-9-17
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pubmed:abstractText |
Teichomycin (teicoplanin) was found to be a mixture of five closely related components of similar polarity, designated T-A2-1, 2, 3, 4 and 5 and of one more polar component, designated T-A3. The separation of the single components was achieved by reverse phase partition chromatography and their physico-chemical and biological properties were compared. The results show that 1) the five major components have the same molecular size of about 1,900; 2) they contain the same ionization function, i.e., a carboxyl group and an amino group which form a zwitterion, and four phenolic groups; 3) they differ in a side aliphatic chain. The component T-A3 is not described.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0021-8820
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
615-20
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6235204-Actinomycetales,
pubmed-meshheading:6235204-Animals,
pubmed-meshheading:6235204-Anti-Bacterial Agents,
pubmed-meshheading:6235204-Chemical Phenomena,
pubmed-meshheading:6235204-Chemistry,
pubmed-meshheading:6235204-Chromatography, High Pressure Liquid,
pubmed-meshheading:6235204-Lethal Dose 50,
pubmed-meshheading:6235204-Magnetic Resonance Spectroscopy,
pubmed-meshheading:6235204-Mice,
pubmed-meshheading:6235204-Microbial Sensitivity Tests,
pubmed-meshheading:6235204-Spectrophotometry,
pubmed-meshheading:6235204-Teicoplanin
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pubmed:year |
1984
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pubmed:articleTitle |
Teichomycins, new antibiotics from Actinoplanes teichomyceticus nov. sp. IV. Separation and characterization of the components of teichomycin (teicoplanin).
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pubmed:publicationType |
Journal Article
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