Linked Life Data

6234757

Source:http://linkedlifedata.com/resource/pubmed/id/6234757

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-7-27
pubmed:abstractText
The sinusoidal analysis method is applied to chemically skinned rabbit psoas preparations, and the effect of Ca ions on exponential processes is determined. The results are compared to the predictions of two classes of models, those in which the binding of Ca2+ to the thin filaments acts as a switch to fully activate a segment of the filament (switch hypothesis), and those in which the binding of Ca2+ results in a graded increase in activity in proportion to the fraction of sites occupied (graded hypothesis). Although qualitative features of our results are in accord with the switch hypothesis, quantitative examination of the results shows that there is an extra process (B'), which produces a W-shaped phase-frequency plot during partial activation. This result is consistent with the assumption that there are two activated states available to the thin filaments of structured muscle.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-2598
pubmed:author
pubmed:issnType
Print
pubmed:volume
170
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
657-72
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
The role of Ca2+ in cross-bridge kinetics in chemically skinned rabbit psoas fibers.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't