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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1984-7-18
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pubmed:abstractText |
Tc-99m-MAA hepatic arterial perfusion scintigraphy ( HAPS ) using a totally implanted drug delivery system was employed for hepatic arterial chemotherapy in 147 patients (335 studies). Complete perfusion of the involved liver was seen in 88% of patients initially [more so in those with normal hepatic vascular anatomy (93%) than those with vascular variants (79%)] and remained good on follow-up. In 67 consecutive patients (95 studies), arteriovenous shunting to the lung ranged from 0.4 to 32% (mean, 6.2% +/- 4.1 S.D.). Uptake at the tip of the catheter was increased in 20% of patients, but good perfusion was usually maintained. A significant decrease in hepatic and/or extrahepatic perfusion associated with a "hot spot" at the tip of the catheter indicated hepatic arterial thrombosis. Extrahepatic perfusion was seen in 14% of cases, usually in the distribution of the stomach, small bowel, and spleen. Significant symptoms of drug toxicity were seen in 70% of patients with extrahepatic perfusion, compared to 19% of those without it.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Implants,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Albumin,
http://linkedlifedata.com/resource/pubmed/chemical/Technetium,
http://linkedlifedata.com/resource/pubmed/chemical/Technetium Tc 99m Aggregated Albumin
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0033-8419
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
152
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
167-72
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6233632-Adult,
pubmed-meshheading:6233632-Aged,
pubmed-meshheading:6233632-Antineoplastic Agents,
pubmed-meshheading:6233632-Drug Implants,
pubmed-meshheading:6233632-Female,
pubmed-meshheading:6233632-Hepatic Artery,
pubmed-meshheading:6233632-Humans,
pubmed-meshheading:6233632-Infusions, Intra-Arterial,
pubmed-meshheading:6233632-Liver Circulation,
pubmed-meshheading:6233632-Liver Neoplasms,
pubmed-meshheading:6233632-Male,
pubmed-meshheading:6233632-Middle Aged,
pubmed-meshheading:6233632-Serum Albumin,
pubmed-meshheading:6233632-Technetium,
pubmed-meshheading:6233632-Technetium Tc 99m Aggregated Albumin
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pubmed:year |
1984
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pubmed:articleTitle |
Hepatic arterial perfusion scintigraphy with Tc-99m-MAA. Use of a totally implanted drug delivery system.
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pubmed:publicationType |
Journal Article
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