Linked Life Data

6228941

Source:http://linkedlifedata.com/resource/pubmed/id/6228941

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-2-24
pubmed:abstractText
We have investigated whether suppression of the allogeneic response after blood transfusion (BT) could be due to inhibition of the production or activity of Interleukin-2 (IL-2), a soluble mediator involved in T lymphocyte proliferation. Reduction of IL-2 production after BT was less frequent than, but significantly associated with, non specific MLR suppression. However, MLR suppressor cells did not inhibit the release of IL-2 from autologous pre-BT lymphocytes. In addition, post-BT soluble suppressor factors of the MLR did not affect the ability of IL-2 to promote cell proliferation. Thus, although MLR suppression after BT is associated with reduced IL-2 production, this is not a major mechanism involved in this effect.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0071-2736
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
349-55
pubmed:dateRevised
2008-2-21
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Interleukin-2 production after blood transfusions in prospective kidney transplant recipients.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't