Linked Life Data

6227464

Source:http://linkedlifedata.com/resource/pubmed/id/6227464

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1984-1-27
pubmed:abstractText
Hair copper and zinc contents were measured in 95 handicapped children aged from 4 to 17 years and 48 age- and sex-matched control children. The patients consisted of 5 groups: children untreated with anticonvulsants (n = 7), those treated with phenytoin and phenobarbital (n = 32), those treated with phenytoin, phenobarbital and diazepam (n = 18), those treated with diazepam alone (n = 16) and those treated with phenobarbital alone (n = 12). The patients were all institutionalized in the same medical care unit and received the same diet, containing decreased amounts of copper (75% of control) and sufficient amounts of zinc. The patients belonging to all of the 5 groups had less amounts of hair copper (p less than 0.05) and erythrocyte hemoglobin (p less than 0.01) in comparison to controls. The patients receiving diazepam alone or in addition to other anticonvulsants had significantly less hair zinc content (p less than 0.05) in comparison to controls or other patient groups. Thus, diazepam seemed to have an adverse effect, producing zinc deficiency.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0379-8305
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
381-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Hair copper and zinc concentrations in handicapped children treated with anticonvulsants.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't