Linked Life Data

6227260

Source:http://linkedlifedata.com/resource/pubmed/id/6227260

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-12-20
pubmed:abstractText
Experimental tumor cell lines were used to show that in the presence of 5-fluorodeoxyuridine (FdUrd), the rate of DNA synthesis remains unaltered as long as a saturating concentration of thymidine is present. This unimpeded rate of DNA synthesis in combination with FdUrd-blocked de novo thymidylate synthesis makes it possible to accurately measure the total rate of increase of DNA using tritiated thymidine of known specific activity. The observed amount of incorporated tritiated thymidine is in excellent agreement with the calculated theoretical maximal incorporation in cultures with exponentially increasing DNA and cell number.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0003-2697
pubmed:author
pubmed:issnType
Print
pubmed:volume
133
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
136-41
pubmed:dateRevised
2000-12-18
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Rate of DNA synthesis in exponentially growing cell lines in the presence and absence of antimetabolites.
pubmed:publicationType
Journal Article