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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1983-9-20
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pubmed:abstractText |
The antigen-specific T suppressor cell clone HF1 isolated from a CBA/J mouse made tolerant by low doses of bovine serum albumin has suppressive and cytolytic activity. The analysis of the latter gave the following results. Natural killer (NK)-sensitive YAC-1 (H-2a) and RBL-5 (H-2b) target cells are lysed whereas other NK targets, like EL4 (H-2b) or the human K562 cell line are resistant. Cytolytic activity is not antibody mediated. Its inhibition by sugar phosphate or monoclonal antibodies against LFA-1 antigens is such that HF1 can neither by typed as T killer nor as NK cells. It seems to represent a distinct T lymphocyte type.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0014-2980
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
551-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6223825-Animals,
pubmed-meshheading:6223825-Cell Line,
pubmed-meshheading:6223825-Clone Cells,
pubmed-meshheading:6223825-Cytotoxicity, Immunologic,
pubmed-meshheading:6223825-Humans,
pubmed-meshheading:6223825-Killer Cells, Natural,
pubmed-meshheading:6223825-Leukemia, Experimental,
pubmed-meshheading:6223825-Leukemia, Lymphoid,
pubmed-meshheading:6223825-Lymphoma,
pubmed-meshheading:6223825-Mice,
pubmed-meshheading:6223825-Mice, Inbred CBA,
pubmed-meshheading:6223825-Microscopy, Electron,
pubmed-meshheading:6223825-T-Lymphocytes, Regulatory
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pubmed:year |
1983
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pubmed:articleTitle |
Characterization of the cytolytic activity of a cloned antigen-specific T suppressor cell derived from a tolerant CBA/J mouse.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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