Linked Life Data

6220870

Source:http://linkedlifedata.com/resource/pubmed/id/6220870

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-6-10
pubmed:abstractText
Twenty healthy subjects (7 men and 13 women) with average baseline P. acnes counts equal to or greater than 1.0 x 10(5) were treated twice a day for eleven days in a randomized, double-blind study with either erythromycin 1.5 percent topical solution or clindamycin phosphate 1.0 percent topical solution. P. acnes counts and free fatty acid (FFA) measurements were performed before treatment, and on Days 4 and 11 of treatment. Statistically significant reductions in P. acnes counts were produced in both groups over the course of the study. There were no statistically significant changes in FFA, free fatty acid/fatty ester (FFA/FE) ratios or triglyceride levels. With erythromycin there were greater reductions in FFA and FFA/FE ratios and greater increases in triglycerides than with the clindamycin group, but the differences between the treatment groups were not significant. No adverse reactions were reported.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0011-4162
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
339-42
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Effects of treatment with erythromycin 1.5 percent topical solution or clindamycin phosphate 1.0 percent topical solution on P. acnes counts and free fatty acid levels.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial