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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1983-4-7
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pubmed:databankReference | |
pubmed:abstractText |
The 3612-bp DNA sequence of the phage lambda P-Q (ninR) region contains a series of nine open reading frames in a distinctly overlapping pattern: ATGA sequence modules occur at the boundaries of consecutive genes and are able to serve both as terminator (TGA) and (re)initiator (ATG) codons for most of the adjacent frames. Together with genes O, P, and Q, the newly detected ren and ninA through ninH constitute a series of twelve closely linked genes in the pR operon. Based upon the available evidence for several of the nin proteins, and on plasmid expression data, we conclude that at least the larger nin genes, and probably all of the newly detected open reading frames code for proteins. The nin5 deletion of 2803 bp is a frame-to-frame fusion of ren and ninH, and covers the t R2 termination signal located near its left boundary, immediately behind the ren gene. The possible significance of the observed chain of closely interlinked genes for the regulation of Q expression is discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0378-1119
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-38
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:6219042-Bacteriophage lambda,
pubmed-meshheading:6219042-Base Sequence,
pubmed-meshheading:6219042-DNA, Viral,
pubmed-meshheading:6219042-Genes, Viral,
pubmed-meshheading:6219042-Genetic Linkage,
pubmed-meshheading:6219042-Protein Biosynthesis,
pubmed-meshheading:6219042-Transcription, Genetic
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pubmed:year |
1982
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pubmed:articleTitle |
A chain of interlinked genes in the ninR region of bacteriophage lambda.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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