Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-10-29
pubmed:abstractText
Preactivation of feline peripheral blood mononuclear cells with mitogenic doses of concanavalin A resulted in suppression of proliferation when these cells were cocultured with untreated autologous cells. The degree of suppression was directly proportional to the preactivation time and ratio of preactivated to untreated cells. The generation, but not the activity, of the suppressor cells was dependent on DNA and protein synthesis. Pokeweed mitogen and phytohemagglutinin were also shown to be capable of inducing suppressor cell activity. Suppression was also observed in allogeneic cocultures. Supernatants from concanavalin A-preactivated cell cultures did not suppress proliferation of untreated cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0020-5915
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
148-55
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Generation of concanavalin A-induced suppressor cells in the cat.
pubmed:publicationType
Journal Article