Linked Life Data

6212539

Source:http://linkedlifedata.com/resource/pubmed/id/6212539

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-9-17
pubmed:abstractText
In an attempt to locate precisely the sites on human IgG responsible for binding to monocytes and macrophages, synthetic peptides representative of sequences of the human gamma-chain have been used as potential inhibitors of human [125I]IgG1 binding to human monocytes and mouse macrophages. One peptide, comprising the sequence of Tyr407--Arg416 of the C gamma 3 domain, showed the same maximum inhibition of [125I]IgG binding to mouse macrophages as unlabelled IgG. Two peptides derived from sequences in the C gamma 2 domain were shown to exhibit limited inhibition of Igg binding to homologous human monocytes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0165-2478
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
215-21
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
The use of synthetic gamma-chain peptides in the localization of the binding site(s) on human IgG1 for the Fc receptors of homologous monocytes and heterologous mouse macrophages.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't