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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1984-11-28
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pubmed:abstractText |
The fine structure of the antigenic determinants of herpes simplex virus type 1 and 2 glycoprotein D (gD) was analyzed to determine whether structural differences underlie the differential immunogenicity of these glycoproteins. A region common to herpes simplex virus type 1 and 2 gD (amino acid residues 11 to 19) and two sites specific for herpes simplex virus type 2 gD (one determined by proline at position 7, the other determined by asparagine at position 21) were localized within the N-terminal 23 amino acids of gD by synthesis of peptides and comparison of their cross-reactivity with antisera raised to herpes simplex virus type 1 and 2 gD. The secondary structure of these peptides, as predicted by computer analysis, is discussed in relation to their immunogenicity.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-4358939,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-4358940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-5480159,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6167991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6172383,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6176725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6192445,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6197535,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6255183,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6277788,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6284965,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6289440,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6292496,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6304705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6321120,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-6323270,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-80458,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6208376-84683
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
431-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1984
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pubmed:articleTitle |
Fine structure analysis of type-specific and type-common antigenic sites of herpes simplex virus glycoprotein D.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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