Linked Life Data

6207894

Source:http://linkedlifedata.com/resource/pubmed/id/6207894

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-12-19
pubmed:abstractText
[3H]substance P binding was studied in the intermediolateral cell column and striatum in the rat using slide-mounted sections. The intermediolateral cell column had a single high affinity binding component with a dissociation constant, Kd = 1.45 nM and the number of sites, Bmax = 18.1 fmol per mg protein. The striatum had a Kd = 0.77 nM and a Bmax = 23.5 fmol per mg protein. The relative potency of various substance P-like tachykinins in displacing [3H]substance P suggested that both these areas may contain a substance P-P (for physalaemin) receptor subtype. (D-Pro4, D-Trp7,9)substance P(4-11), a substance P antagonist, has a relatively low affinity (micromolar range) in both these areas.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
311
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
144-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
[3H]substance P binding in the intermediolateral cell column and striatum of the rat.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't