Linked Life Data

6205133

Source:http://linkedlifedata.com/resource/pubmed/id/6205133

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1984-9-6
pubmed:abstractText
The purpose of this study was to determine if polysaccharide dextrans would pass through intact-nonkeratinized and induced-keratinized sulcular epithelia in monkeys. Dextran penetration through normally keratinized oral gingival epithelium also was evaluated in the same gingival specimens. Each of three Rhesus monkeys received a thorough prophylaxis 1 week prior to the experiment. During this week, the monkeys also received daily IV injections of Achromycin. After the antibiotic treatment, the teeth were polished and cleaned with a rubber cup using prophylactic paste for 2 consecutive months, as follows: (1) the right maxillary and mandibular teeth received daily prophylaxes on weekdays and (2) the left maxillary and mandibular teeth received one prophylaxis weekly. These frequencies of plaque removal on one-half of the mouth maintained clinically healthy gingiva and produced keratinization of the sulcular epithelium. At the end of the 2-month prophylaxes, a 5% solution of dextrans derived from Leuconostoc mesenteroides was applied topically to the gingiva once daily for 3 consecutive weeks. During this time, the monkeys continued having dental prophylaxes following the previous time schedule. The study showed that induced-keratinized sulcular epithelium as well as normally keratinized oral gingival epithelium resisted penetration of dextrans, whereas intact-nonkeratinized sulcular epithelium apparently lacked a surface layer resistant to penetration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0022-3492
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
424-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Dextran penetration through nonkeratinized and keratinized epithelia in monkeys.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S.