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pubmed:abstractText |
Fourteen of 80 patients (17.5 per cent) who underwent elective craniotomy preceded by a strict pre-operative routine of skin decontamination contracted postoperative wound infection. Most of the infections were probably from endogenous sources and from eight of the wounds low-virulent resident skin bacteria, Propionibacterium acnes and/or Staphylococcus epidermidis, were isolated. Since thorough pre-operative preparation of the skin did not reduce the incidence of infection to an acceptable level, antibiotic prophylaxis might be indicated in this type of surgery.
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