Linked Life Data

6204753

Source:http://linkedlifedata.com/resource/pubmed/id/6204753

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7-8
pubmed:dateCreated
1984-9-20
pubmed:abstractText
Thirty-three patients with stage III-IV squamous cell carcinoma of the head and neck previously untreated with chemotherapy or radiotherapy were given a multidrug cytotoxic regimen, VBM (vincristine, bleomycin, and methotrexate), in combination with radical radiotherapy. Of the 32 evaluable patients, 11 (34.4%) achieved clinical complete response with negative biopsy, 15 (46.8%) achieved partial response, three (9.4%) had no change, and three (9.4%) had disease progression. At 30 months, the actuarial survival rate for complete responders with negative biopsy was 62.2% and the overall survival rate was 30.8%. Hematologic and gastrointestinal toxicity was moderate, but one patient developed life-threatening mucositis and one patient died due to acute renal failure. Our data do not confirm prior more favorable results obtained with the same treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0361-5960
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1019-21
pubmed:dateRevised
2006-4-24
pubmed:meshHeading
pubmed:articleTitle
Multidrug chemotherapy (vincristine, bleomycin, and methotrexate [VBM]) with radiotherapy in stage III-IV squamous cell carcinoma of the head and neck.
pubmed:publicationType
Journal Article