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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1984-5-30
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pubmed:abstractText |
Agents such as TEA+ or CS+ ions, these last ions instead of K+ ions in poor K extracellular solution, known to reduce or abolish the inwardly rectifying channel in many preparations produced no effect in crayfish muscle membrane By contrast, poor Cl extracellular solution (Cl- ions were replaced by CH3OSO3- ions) blocked the inward current activated by hyperpolarizing pulses and produced an increase of the resting potential. Niflumic acid is a agent which inhibited the inward going rectification of the crayfish muscle membrane. Apparent dissociation constant of niflumic acid with membrane sites was equal to about 6 X 10(-8) M; this value corresponds to that given by Cousin & Motais (1979) concerning translocation of Cl- ions in the membrane of red cells. Activation of the inward going rectification in the crayfish membrane is responsible of an inward current carried by Cl- ions.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0003-9799
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
269-77
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6202258-Animals,
pubmed-meshheading:6202258-Astacoidea,
pubmed-meshheading:6202258-Chlorides,
pubmed-meshheading:6202258-Membrane Potentials,
pubmed-meshheading:6202258-Membranes,
pubmed-meshheading:6202258-Microelectrodes,
pubmed-meshheading:6202258-Muscles,
pubmed-meshheading:6202258-Nicotinic Acids,
pubmed-meshheading:6202258-Niflumic Acid,
pubmed-meshheading:6202258-Potassium
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pubmed:year |
1983
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pubmed:articleTitle |
[Inhibition, by an amphiphilic substance, niflumic acid, of the inward rectification of the crustacean muscle fiber].
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pubmed:publicationType |
Journal Article,
English Abstract
|