Linked Life Data

6200092

Source:http://linkedlifedata.com/resource/pubmed/id/6200092

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-4-12
pubmed:abstractText
Four different isolates of Aleutian disease virus have been compared electrophoretically and serologically. These were the DK and Utah 1 isolates, known as highly virulent strains, the Pullman isolate, known as a low virulent strain and the avirulent ADV-G isolate, which is the only strain grown in cell culture. ADV-G was shown to migrate in agarose electrophoresis 22 per cent slower than the other strains. Several murine monoclonal antibodies were prepared against each of the isolates. Each one reacted with all 4 of the isolates, but a few showed higher affinity for some of the isolates. Competitive RIA analyses were also performed, and these studies indicated some serological differences between the 4 strains. It is concluded that ADV-G polypeptides are chemically different but immunologically cross-reacting with the polypeptides present on the field ADV strains. It is suggested that the small serological differences seen between the field strains might be caused by slightly different in vivo proteolytic degradation of the viral capsid proteins and thus might not be taken as an indication of strain variation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0304-8608
pubmed:author
pubmed:issnType
Print
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11-22
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Serological analyses of different mink Aleutian disease virus strains.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't