Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-4-20
pubmed:abstractText
Monoclonal antibodies 35S and 55S, specific for herpes simplex virus type 1 (HSV-1) glycoproteins gB and gD respectively, were found to react with infected cell membranes but not cell-free virions. This indicates that the spectrum of viral determinants detectable on the infected cell surface is not identical to that detectable on the virion envelope. The monoclonal antibody 35S could promote recovery from ocular HSV-1 infection in mice. Thus, antibody reactive with infective cell-specific determinants can play a significant role in host resistance to HSV-1 infection.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0022-1317
pubmed:author
pubmed:issnType
Print
pubmed:volume
65 ( Pt 3)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
657-61
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Identification of infected cell-specific monoclonal antibodies and their role in host resistance to ocular herpes simplex virus type 1 infection.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.