Linked Life Data

6197980

Source:http://linkedlifedata.com/resource/pubmed/id/6197980

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1984-3-19
pubmed:abstractText
It has been shown that a variety of stressful procedures, such as immobilization and footshock, can induce a significant degree of analgesia in mice. In addition, it has been shown that for some, but not all, stressful treatments, the analgesic effect is mediated via endogenous opioids. This report describes the effects of substance P, administered systemically, on both opioid-mediated immobilization-induced analgesia and non-opioid footshock-induced analgesia. Substance P completely blocked the opioid-mediated form of stress-induced analgesia while having no effect on the non-opioid form. Exogenous substance P appears to interact with endogenous opioid pain-suppressing systems.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0166-4328
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
375-82
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Prevention of stress-induced analgesia by substance P.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.