Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1984-2-14
pubmed:abstractText
The majority, and perhaps all, of the genes for human U1 small nuclear RNA (U1 RNA) were shown to be located on the short arm of human chromosome 1. These genes were mapped by Southern blot analysis of DNA from rodent-human somatic cell hybrids, using the 5' region of a human U1 RNA gene as a human-specific probe. This probe hybridized to DNA fragments present only in digests of total human DNA or to the DNAs of cell lines which contained human chromosome 1. The major families of human U1 RNA genes were identified, but some human genes may have gone undetected. Also, the presence of a few U1 RNA genes on human chromosome 19 could not be ruled out. In spite of the lack of extensive 5'-flanking-region homology between the human and mouse U1 RNA genes, the genes of both species were efficiently transcribed in the hybrid cells, and the U1 RNAs of both species were incorporated into specific ribonucleoprotein particles.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-1195397, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-14168277, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-182062, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-231109, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-316537, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-4114702, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-4354250, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-438299, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-4577761, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-4633729, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-5133546, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-5325727, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-5963888, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6085956, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6162401, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6165010, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6179629, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6179630, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6180116, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6183277, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6188110, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6190611, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6191037, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6192042, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6194507, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6259625, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6573776, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-66325, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-6969453, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-7018693, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-7273954, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-7350544, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-7363327, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-752471, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-881736, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-893544, http://linkedlifedata.com/resource/pubmed/commentcorrection/6197626-978727
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0270-7306
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2211-20
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
U1 small nuclear RNA genes are located on human chromosome 1 and are expressed in mouse-human hybrid cells.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't