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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1984-2-15
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pubmed:abstractText |
An antigenic determinant capable of inducing type-common herpes simplex virus (HSV)-neutralizing antibodies has been located on glycoprotein D (gD) of HSV type 1 (HSV-1). A peptide of 16 amino acids corresponding to residues 8 to 23 of the mature glycoprotein (residues 33 to 48 of the predicted gD-1 sequence) was synthesized. This peptide reacted with an anti-gD monoclonal antibody (group VII) previously shown to neutralize the infectivity of HSV-1 and HSV-2. The peptide was also recognized by polyclonal antibodies prepared against purified gD-1 but was less reactive with anti-gD-2 sera. Sera from animals immunized with the synthetic peptide reacted with native gD and neutralized both HSV-1 and HSV-2.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-176453,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-229263,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-388439,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-4137226,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-4344251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-4358939,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-4358940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-4850204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-5443684,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-5963888,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6159137,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6167991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6172383,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6174636,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6176725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6181415,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6271681,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6284965,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6286849,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6289440,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6290390,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6292092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-6317892,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-667015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-7045684,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-80458,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-84683,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6197535-86497
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
102-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6197535-Animals,
pubmed-meshheading:6197535-Antibodies, Monoclonal,
pubmed-meshheading:6197535-Antibodies, Viral,
pubmed-meshheading:6197535-Antigens, Viral,
pubmed-meshheading:6197535-Epitopes,
pubmed-meshheading:6197535-Glycoproteins,
pubmed-meshheading:6197535-Herpes Simplex,
pubmed-meshheading:6197535-Peptides,
pubmed-meshheading:6197535-Viral Interference,
pubmed-meshheading:6197535-Viral Proteins
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pubmed:year |
1984
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pubmed:articleTitle |
Localization and synthesis of an antigenic determinant of herpes simplex virus glycoprotein D that stimulates the production of neutralizing antibody.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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