Linked Life Data

6197294

Source:http://linkedlifedata.com/resource/pubmed/id/6197294

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-2-24
pubmed:abstractText
We investigated the localization of LH and FSH cells within the pituitary glands of normal adult rats. Groups of four female rats were decapitated at one of five different times during the estrous cycle. Four male rats were also decapitated. Paired horizontal flip-flopped serial paraplast sections from the dorsal, middle, and ventral portions of each pituitary gland were stained. For each pair, one section was stained with antirat LH-S4 and the other section with antirat FSH-S7, by the unlabeled antibody peroxidase-antiperoxidase method. All immunoreactive cells were counted, and the area of pars distalis in each section was determined. We studied the spatial distribution of gonadotrophs within the sections and determined if a polarization along the antero-posterior axis existed. In the "sex zone" of the pars distalis, the cross-sectional area of LH cells and the percentages of LH cells that also contained FSH and vice versa were determined and compared with those obtained from the entire pars distalis. Additional sections were stained for TSH, ACTH, GH, or PRL, and the distribution of stained cells was compared with that of those that stained for LH or LH/FSH, particularly in the sex zone and in the pars intermedia. The results indicate that 1) gonadotrophs are more evenly distributed dorsoventrally within the pars distalis of male rats than in that of female rats; 2) an antero-posterior polarity in gonadotropic distribution is more pronounced in male rats than in female rats; 3) gonadotrophs containing only LH are less numerous in male than female rats, and in the female tend to be centrally located within the pars distalis; 4) the sex zone contains PRL cells and gonadotrophs, and the percentages of gonadotrophs that contain LH or LH and FSH are not different from those of the entire pars distalis; 5) LH, and occasionally LH/FSH cells, are present between lobules of immunoreactive ACTH cells in the pars intermedia; and 6) LH cells in the pars intermedia are smaller than those in the sex zone or entire pars distalis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0013-7227
pubmed:author
pubmed:issnType
Print
pubmed:volume
114
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
397-406
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
The localization of gonadotrophs in normal adult male and female rats.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't