Linked Life Data

6194883

Source:http://linkedlifedata.com/resource/pubmed/id/6194883

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1983-12-20
pubmed:abstractText
The antibody Fl shows preferential reactivity with adult erythrocytes over newborn erythrocytes, and its reactivity is abolished by sialidase treatment of the erythrocyte. The antibody was found to recognize binary determinants linked to the branched lacto-N-isooctaosylceramide (formula; see text) The presence of an N-acetylneuraminyl group at one end and L-fucosyl group at the other end is essential for the reactivity of the antibody. A substitution at the penultimate D-galactosyl residue of one of the chains with an alpha-D-(1 leads to 3)-linked 2-acetamido-2-deoxygalactosyl or galactosyl group did not inhibit the reactivity of the antibody. The new blood group A- and B-active, branched gangliosides are also isolated and characterized.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0008-6215
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
120
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
143-57
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Characterization of an epitope (determinant) structure in a developmentally regulated glycolipid antigen defined by a cold agglutinin Fl, recognition of alpha-sialosyl and alpha-L-fucosyl groups in a branched structure.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.