rdf:type |
|
lifeskim:mentions |
umls-concept:C0003241,
umls-concept:C0027950,
umls-concept:C0034580,
umls-concept:C0037791,
umls-concept:C0041485,
umls-concept:C0061472,
umls-concept:C0205232,
umls-concept:C0243071,
umls-concept:C0332283,
umls-concept:C1305923,
umls-concept:C1648700,
umls-concept:C1705176,
umls-concept:C1705178,
umls-concept:C1883254
|
pubmed:issue |
2
|
pubmed:dateCreated |
1983-11-23
|
pubmed:abstractText |
The fine specificity of antibodies against (T,G)-A--L and its ordered analogs (T-T-G-G)-A--L and (T-G-T-G)-A--L was studied. Fifty percent of the antibodies against (T,G)-A--L are directed toward the T-T-G-G determinants and 19% against T-G-T-G-like determinants. The rest of the antibody response to (T,G)-A--L is directed against determinants which exist in (T,G)-A--L but are not cross-reactive with either T-T-G-G- or T-G-T-G-like determinants. Although (T-T-G-G)-A--L and (T-G-T-G)-A--L differ only in the sequence of tyrosine and glutamic acid in their side chains, no crossreactivity was observed between antibodies toward the two ordered polypeptide antigens.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0003-9861
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
225
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
446-50
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6194752-Animals,
pubmed-meshheading:6194752-Antibodies,
pubmed-meshheading:6194752-Antigen-Antibody Complex,
pubmed-meshheading:6194752-Cross Reactions,
pubmed-meshheading:6194752-Epitopes,
pubmed-meshheading:6194752-Immune Sera,
pubmed-meshheading:6194752-Kinetics,
pubmed-meshheading:6194752-Mice,
pubmed-meshheading:6194752-Mice, Inbred C3H,
pubmed-meshheading:6194752-Peptides,
pubmed-meshheading:6194752-Radioimmunoassay,
pubmed-meshheading:6194752-T-Lymphocytes, Helper-Inducer
|
pubmed:year |
1983
|
pubmed:articleTitle |
Fine specificity of antibodies to the synthetic polypeptide poly(L-tyrosine, L-glutamic acid)-poly(DL-alanine)--poly(L-lysine) and its ordered analogs as followed by solid-phase radioimmunoassay.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|