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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1983-8-17
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pubmed:abstractText |
A computerized method for predicting the locations of protein antigenic determinants is presented, which requires only the amino acid sequence of a protein, and no other information. This procedure has been used to predict the major antigenic determinant of the hepatitis B surface antigen, as well as antigenic sites on a series of test proteins of known antigenic structure [Hopp & Woods (1981) Proc. natn. Acad. Sci. U.S.A. 78, 3824-3828.] The method is suitable for use in smaller personal computers, and is written in the BASIC language, in order to make it available to investigators with limited computer experience and/or resources. A means of locating multiple antigenic sites on a homologous series of proteins is demonstrated using the influenza hemagglutinin as an example.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0161-5890
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
483-9
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:6191210-Amino Acid Sequence,
pubmed-meshheading:6191210-Computers,
pubmed-meshheading:6191210-Epitopes,
pubmed-meshheading:6191210-Hemagglutinins, Viral,
pubmed-meshheading:6191210-Hepatitis B Surface Antigens,
pubmed-meshheading:6191210-Methods,
pubmed-meshheading:6191210-Models, Chemical,
pubmed-meshheading:6191210-Orthomyxoviridae,
pubmed-meshheading:6191210-Proteins
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pubmed:year |
1983
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pubmed:articleTitle |
A computer program for predicting protein antigenic determinants.
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pubmed:publicationType |
Journal Article
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