Linked Life Data

6189669

Source:http://linkedlifedata.com/resource/pubmed/id/6189669

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-7-29
pubmed:abstractText
The inclusion of normal guinea-pig serum in neutralisation reactions involving foot-and-mouth disease virus (FMDV) increased the neutralisation titre and rate of neutralisation by guinea-pig antiserum derived from animals convalescent from FMDV. Such inclusion had little or no effect on neutralisation involving guinea-pig antiserum collected early in infection or early or convalescent bovine antisera. Higher neutralisation titres and more rapid neutralisation were found from assay in bovine thyroid cells than in IB-RS-2 cells. Not all the increase in neutralising activity was removed by heating at 56 degrees C, indicating that other factors in addition to complement were responsible. In some tests a virus fraction resisting neutralisation was found and, when rabbit anti-guinea-pig gamma-globulin was added, an increase in neutralisation resulted, suggesting that most of the persistent virus fraction was due to the presence of infective virus-antibody complexes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0147-9571
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
161-9
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
The influence of normal guinea-pig serum and tissue culture assay system on foot-and-mouth disease virus neutralisation.
pubmed:publicationType
Journal Article, Comparative Study