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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8331
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pubmed:dateCreated |
1983-5-27
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pubmed:abstractText |
Between 1979 and 1982, 69 men with metastatic malignant teratoma completed sequential combination chemotherapy (POMB/ACE). Although two-thirds of these patients initially had advanced and bulky disease, life-table analysis projects a survival of 83%. Multivariate analysis indicates that the strongest predictor of survivals is not the clinical and radiological extent of disease but the initial serum concentration of human chorionic gonadotropin (HCG) and alpha-fetoprotein (AFP). In patients presenting with HCG levels below 50 000 IU/l and AFP levels below 500 kU/l the survival in 47 patients was 96%. This contrasts with the survival projected at 56% in 22 patients presenting with tumour markers at higher concentrations.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0140-6736
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
948-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6188011-Antineoplastic Agents,
pubmed-meshheading:6188011-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:6188011-Bleomycin,
pubmed-meshheading:6188011-Chorionic Gonadotropin,
pubmed-meshheading:6188011-Cyclophosphamide,
pubmed-meshheading:6188011-Cytarabine,
pubmed-meshheading:6188011-Dactinomycin,
pubmed-meshheading:6188011-Drug Therapy, Combination,
pubmed-meshheading:6188011-Etoposide,
pubmed-meshheading:6188011-Humans,
pubmed-meshheading:6188011-Lung Neoplasms,
pubmed-meshheading:6188011-Male,
pubmed-meshheading:6188011-Mediastinal Neoplasms,
pubmed-meshheading:6188011-Methotrexate,
pubmed-meshheading:6188011-Neoplasm Staging,
pubmed-meshheading:6188011-Prognosis,
pubmed-meshheading:6188011-Retroperitoneal Neoplasms,
pubmed-meshheading:6188011-Teratoma,
pubmed-meshheading:6188011-Testicular Neoplasms,
pubmed-meshheading:6188011-Vincristine,
pubmed-meshheading:6188011-alpha-Fetoproteins
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pubmed:year |
1983
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pubmed:articleTitle |
Further advances in the management of malignant teratomas of the testis and other sites.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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