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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1983-1-7
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pubmed:abstractText |
Leucocytes from normal non-allergic donors were passively sensitized with sixty-five atopic sera that contained IgE directed against house dust mite (HDM) or guinea-pig dander (GPD). In no serum was there any IgE with an abnormal basophil anaphylactic-sensitizing activity. In sera from patients hypersensitive to GPD, both GPD-specific IgE and IgG4 were measured. A significant correlation was found between the GPD-IgE RAST and the basophil-sensitizing capacity of GPD-positive sera, but no correlation was found between this sensitizing capacity and the GPD-IgG4 RAST. Leucocytes were passively sensitized with serum mixtures that contained the same amounts of total and HDM-specific IgE; these mixtures differed as to sensitizing activity. It is unclear whether this variation is due to differences in IgE or to influences of other factors in serum.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Allergens,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Dust,
http://linkedlifedata.com/resource/pubmed/chemical/Epitopes,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin E,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0009-9090
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
451-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6183022-Allergens,
pubmed-meshheading:6183022-Antibodies,
pubmed-meshheading:6183022-Basophils,
pubmed-meshheading:6183022-Dust,
pubmed-meshheading:6183022-Epitopes,
pubmed-meshheading:6183022-Humans,
pubmed-meshheading:6183022-Immunization, Passive,
pubmed-meshheading:6183022-Immunoglobulin E,
pubmed-meshheading:6183022-Immunoglobulin G,
pubmed-meshheading:6183022-Mites
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pubmed:year |
1982
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pubmed:articleTitle |
Allergen-specific IgE and IgG4 antibody levels in sera and the capacity of these sera to sensitize basophil leucocytes in vitro.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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