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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1982-12-21
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pubmed:abstractText |
The concentration of beta 2-microglobulin (beta 2-m) in parotid saliva and sera from 13 adult hypogammaglobulinaemic subjects and in parotid saliva from 7 normal adults was determined by radioimmunoassay. Parotid and submandibular/sublingual saliva was collected from four normal and one hypogammaglobulinaemic subject in unstimulated and stimulated samples, and concentrations of IgA and beta 2-m were determined. The beta 2-m concentration in parotid saliva from hypogammaglobulinaemic subjects was 0.50 mg/l (0.2-1.1) and in normal adults 0.41 mg/l (0.2-0.9). In parotid saliva, the concentration of beta 2-m was negatively correlated with the flow rate, whereas in submandibular/sublingual a positive correlation was seen. Serum levels of beta 2-m in hypogammaglobulinaemic subjects were within the normal range of healthy adults. Gel filtration of saliva separated beta 2-m from IgA and from high molecular weight agglutinins. Beta 2-m was eluted as one single peak.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0003-9969
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
679-82
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6182864-Adult,
pubmed-meshheading:6182864-Agammaglobulinemia,
pubmed-meshheading:6182864-Beta-Globulins,
pubmed-meshheading:6182864-Chromatography, Agarose,
pubmed-meshheading:6182864-Humans,
pubmed-meshheading:6182864-Immunoglobulin A,
pubmed-meshheading:6182864-Parotid Gland,
pubmed-meshheading:6182864-Saliva,
pubmed-meshheading:6182864-Salivation,
pubmed-meshheading:6182864-Submandibular Gland,
pubmed-meshheading:6182864-beta 2-Microglobulin
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pubmed:year |
1982
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pubmed:articleTitle |
beta 2-Microglobulin in saliva and its relation to flow rate in different glands in man.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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