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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1982-12-21
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pubmed:abstractText |
The cross reactivity of two currently used substance P (SP) antisera (K 16 and K 25) with various analogues of SP, partial sequences of SP and other naturally occurring peptides were tested in a radioimmunoassay system. Both antisera were found to be C-terminal directed, this tendency being most pronounced for antiserum K 16. The capacity of antiserum K 25 to bind various SP-related peptides correlated to the previously described biological activity of these peptides on the isolated guinea pig ileum. The results thus indicate that this antiserum binds to a biologically active part of the SP-molecule.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
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pubmed:issn |
0001-6772
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
53-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:6182748-Amino Acid Sequence,
pubmed-meshheading:6182748-Antigen-Antibody Reactions,
pubmed-meshheading:6182748-Binding Sites, Antibody,
pubmed-meshheading:6182748-C-Peptide,
pubmed-meshheading:6182748-Cross Reactions,
pubmed-meshheading:6182748-Immune Sera,
pubmed-meshheading:6182748-Peptide Chain Termination, Translational,
pubmed-meshheading:6182748-Radioimmunoassay,
pubmed-meshheading:6182748-Substance P
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pubmed:year |
1982
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pubmed:articleTitle |
Characterization of two substance P antisera.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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