Linked Life Data

61809

Source:http://linkedlifedata.com/resource/pubmed/id/61809

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9 pt.1
pubmed:dateCreated
1976-12-30
pubmed:abstractText
Following formation of hyperplastic nodules, some areas of presumptive preneoplastic liver parenchyma show intense cytoplasmic RNA staining. This hyperbasophilia is not associated with increased ribosome content. Histochemical localization of metallic cations remaining after Carnoy fixation implies an inverse relationship with toluidine blue staining. In liver tissue fixed with potassium pyroantimonate, more inorganic cation precipitation occurs in nucleic of hyperbasophilic foci and hepatomas than within surrounding liver parenchyma. Electron microscopic observations of hyperbasophilic hepatocytes revealed large deposits of cation antimonate within nucleoli and nuclear interchromatin areas and finer deposits in apparent association with cytoplasmic ribosomes. Thus, differences in basophilia may reflect variations in cation levles. Since hyperbasophilic foci show increased thymidine incorporation, cell proliferation may be correlated with histochemically detected alterations of intracellular cations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0008-5472
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3086-93
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Intracellular cations and basophilia in rat liver parenchyma during azo dye carcinogenesis.
pubmed:publicationType
Journal Article